During the denture setup process, which aspect primarily influences the overall esthetics?

The position of the midline plays a crucial role in the overall esthetics of denture setup because it directly affects the symmetry and alignment of the teeth in the smile. When the midline is properly positioned, it enhances the facial harmony and ensures that the arrangement of the teeth appears natural and well-balanced in relation to the patient's facial features. A correctly aligned midline not only contributes to the appearance of the dentures but also impacts the functional aspects of mastication and phonetics.

Tooth size, while important, is not as directly influential on esthetics as the midline's position. The color of the denture base can enhance or detract from the overall look, but it is secondary to the midline's contribution to facial symmetry. Arch form can affect fit and function, but alignment concerning the midline is the key factor for establishing an aesthetically pleasing denture setup. Hence, the position of the midline is fundamental in ensuring the dentures not only function well but also provide a visually appealing outcome for the patient.