In a case of a mass found in the mandibular angle, which condition is most likely?

The presence of a mass in the mandibular angle often raises suspicion for various conditions, but a pleomorphic adenoma, particularly when associated with the salivary glands, is the most likely scenario in this context. Pleomorphic adenoma, also known as a benign mixed tumor, frequently arises in the major salivary glands, particularly the parotid gland, which is situated near the mandibular angle.

These tumors can manifest as painless swellings in this area, leading to the formation of a discernible mass. While other options may also be considered based on their respective characteristics and prevalence, pleomorphic adenoma stands out as it commonly occurs in this anatomical location and tends to be the most frequently diagnosed benign tumor in this region.

In contrast, osteosarcoma, although it can present in the jaw, is less typical for the mandibular angle specifically. Malignant salivary gland tumors, while possible, are generally less common than benign lesions like pleomorphic adenoma in this location. Giant cell tumors are mostly associated with bone and typically present in other locations, making them an unlikely choice for a mass at the mandibular angle.