What antifungal medication is effective against Candida albicans?

Fluconazole is a highly effective antifungal medication used to treat infections caused by Candida albicans, which is a common yeast that can cause various infections in humans, including oral thrush and vulvovaginal candidiasis. Fluconazole works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting their structural integrity and leading to cell death. Its systemic absorption and the ability to penetrate various tissues make it particularly useful in treating candidiasis, especially in cases of severe or recurrent infections.

While other medications like nystatin, clotrimazole, and ketoconazole are also effective against Candida albicans, fluconazole is often preferred for its ease of use, better oral bioavailability, and fewer side effects. Nystatin is primarily used for localized infections and is less effective when a systemic treatment is needed. Clotrimazole is often used topically, making it less suitable for systemic infections, and ketoconazole has largely fallen out of favor due to concerns about its side effects and potential for liver toxicity.