What condition is commonly caused by Cyclosporine?

Gingival hyperplasia is often associated with the use of Cyclosporine, an immunosuppressive medication frequently prescribed for organ transplant patients and certain autoimmune diseases. Cyclosporine can cause an overgrowth of gum tissue due to its effects on fibroblasts and the inflammatory response in the gingiva. This results in an increase in collagen production and a subsequent enlargement of the gums, which is the hallmark of gingival hyperplasia.

The condition typically manifests as swelling of the gums, and patients may find it challenging to maintain good oral hygiene due to the excess tissue. The hyperplastic tissue might also lead to aesthetic concerns and difficulty in eating or speaking effectively.

Understanding the relationship between Cyclosporine and gingival hyperplasia is crucial for clinicians as it emphasizes the need for regular dental check-ups and proper oral hygiene practices for patients receiving this medication. This knowledge helps in identifying early signs of hyperplasia and managing them through dental interventions, ensuring better overall oral health outcomes.