What dental condition is associated with blue sclera?

The dental condition associated with blue sclera is dentinogenesis imperfecta. This condition affects the formation of dentin, one of the primary components of teeth, leading to various dental problems, including discolored teeth that may appear translucent or blue-gray.

The blue sclera is a notable clinical feature due to the underlying skeletal issues and is commonly associated with osteogenesis imperfecta, a genetic disorder that affects collagen formation. Patients with dentinogenesis imperfecta often exhibit fragile teeth that can fracture easily and may also present with the characteristic blue sclera due to the thinness and translucency of the scleral tissue in this condition.

In contrast, amelogenesis imperfecta primarily affects enamel formation, leading to issues like discolored or poorly formed enamel, but does not typically result in blue sclera. Enamel hyperplasia refers to an abnormal increase in enamel production, while gingival hyperplasia involves overgrowth of the gums. Neither of these conditions is associated with any notable changes to the sclera, thus distinguishing them from dentinogenesis imperfecta in this context.