What is a common adverse effect of Nifedipine?

What is a common adverse effect of Nifedipine?

• A. Weight gain
• B. Gingival hyperplasia
• C. Bone density loss
• D. Drowsiness

Answer: (B)

Nifedipine is a calcium channel blocker primarily used in the treatment of hypertension and angina. One of the notable adverse effects associated with the use of Nifedipine is gingival hyperplasia, which is characterized by the overgrowth of gum tissue. This occurs due to the drug's effects on vascular smooth muscle and fibroblasts, leading to increased fibroblast proliferation and collagen production in the gingiva. Gingival hyperplasia is a significant concern for patients, as it not only affects oral hygiene but can also complicate dental care. While other medications, such as certain anticonvulsants like phenytoin and some immunosuppressants, are more commonly associated with this condition, Nifedipine has also been identified as a contributing factor, particularly in long-term use. Weight gain, bone density loss, and drowsiness are not commonly associated adverse effects of Nifedipine. Weight gain is typically not a side effect linked to this medication; in fact, it may have the opposite effect. Additionally, while some medications can lead to bone density changes, Nifedipine does not have a strong association with this issue. Drowsiness, though it can occur with other antih

Nifedipine is a calcium channel blocker primarily used in the treatment of hypertension and angina. One of the notable adverse effects associated with the use of Nifedipine is gingival hyperplasia, which is characterized by the overgrowth of gum tissue. This occurs due to the drug's effects on vascular smooth muscle and fibroblasts, leading to increased fibroblast proliferation and collagen production in the gingiva.

Gingival hyperplasia is a significant concern for patients, as it not only affects oral hygiene but can also complicate dental care. While other medications, such as certain anticonvulsants like phenytoin and some immunosuppressants, are more commonly associated with this condition, Nifedipine has also been identified as a contributing factor, particularly in long-term use.

Weight gain, bone density loss, and drowsiness are not commonly associated adverse effects of Nifedipine. Weight gain is typically not a side effect linked to this medication; in fact, it may have the opposite effect. Additionally, while some medications can lead to bone density changes, Nifedipine does not have a strong association with this issue. Drowsiness, though it can occur with other antih