What is a common side effect of calcium channel blockers like nifedipine?

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Calcium channel blockers, such as nifedipine, are medications primarily used to treat hypertension and other cardiovascular conditions. One notable side effect associated with the use of these drugs is gingival hyperplasia, which is an overgrowth of gum tissue. This condition can occur because calcium channel blockers can alter the normal cellular turnover and growth patterns of gum tissues. It is particularly important for dental professionals to recognize this side effect, as it can impact oral health and hygiene, leading to challenges in maintaining periodontal health.

While increased salivation, dental caries, and pulpal necrosis may be concerns within dental settings, they are not directly associated with the use of calcium channel blockers in the same way gingival hyperplasia is. Increased salivation is less commonly linked to these medications, and dental caries arise primarily from poor oral hygiene and dietary factors rather than being a direct side effect of the drug. Pulpal necrosis is not a well-documented side effect of calcium channel blockers either. Therefore, recognizing gingival hyperplasia is critical for both patient management and preventive care in individuals taking these medications.

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