What is the role of Naloxone in opioid therapy?

Naloxone's primary role in opioid therapy is to reverse opioid overdose. It is an opioid antagonist, meaning that it binds to the same receptors as opioids but does not activate them. When someone experiences an overdose, their respiratory function can become severely compromised due to respiratory depression caused by excessive opioid levels. Administering naloxone can quickly displace the opioids from the receptors, reversing the respiratory depression and restoring normal breathing. This quality makes it a critical emergency medication in situations where opioid overdose is suspected.

The other roles mentioned in the options do not accurately reflect naloxone's purpose. It does not enhance pain relief, reduce opioid tolerance, or increase sedation. Instead, naloxone serves as a crucial intervention to prevent fatal outcomes associated with opioid overdoses, ensuring that individuals receive the timely care they need in emergencies.