What phenomenon is associated with severe cases of angular cheilitis?

In severe cases of angular cheilitis, localized necrosis is a phenomenon that can occur. This condition usually results from several factors, including nutritional deficiencies (such as vitamin B12 or iron), infections (such as fungal or bacterial), or chronic irritation. When the skin at the corners of the mouth becomes severely compromised, it can lead to tissue death (necrosis) in that specific area.

In the context of angular cheilitis, localized necrosis is indicative of a severe inflammatory response. This inflammation may result in the breakdown of skin integrity, leading to ulceration and tissue death. The affected areas can become painful and may ooze, and this is often compounded by secondary infections, making the condition even more severe.

While skin peeling, swelling of the lips, and persistent pain can present symptoms associated with angular cheilitis, they do not encompass the severity of tissue breakdown that localized necrosis signifies. Localized necrosis is a more advanced state of the illness and highlights the critical need for effective treatment to address the underlying causes and prevent further tissue damage.