What substance is responsible for the adherence of plaque to teeth?

The substance responsible for the adherence of plaque to teeth is the pellicle. The pellicle is a thin, acellular layer that forms on the tooth surface shortly after it is cleaned. This layer is primarily composed of proteins and glycoproteins derived from saliva, which allows oral bacteria to attach and colonize on the tooth surface, leading to plaque formation. The presence of the pellicle is crucial because it provides a surface that is conducive to further accumulation of microbial biofilms, enhancing the process of plaque development. Understanding the role of the pellicle in plaque formation is important for dental health, as it contributes to the overall health of the oral environment and can impact conditions like dental caries and periodontal disease.