Which class of drugs is associated with gingival overgrowth?

The class of drugs associated with gingival overgrowth is anticonvulsants. This phenomenon is particularly noted with medications such as phenytoin, which is often prescribed to manage seizure disorders. The exact mechanism by which anticonvulsants cause gingival overgrowth is not completely understood, but it is believed to involve alterations in the metabolism of fibroblasts and inflammatory responses leading to tissue hyperplasia.

Gingival overgrowth can manifest as swelling and enlargement of the gums, which can cause discomfort and complicate oral hygiene, potentially leading to further dental issues. It's important for healthcare providers to monitor patients on these medications for signs of gingival overgrowth and to provide guidance on oral hygiene practices to mitigate the risk.

Other classes such as corticosteroids, antidepressants, and antipsychotics are not generally associated with such significant gingival changes, making anticonvulsants the correct choice in this context.