Which disease is known to significantly affect the wear of complete dentures?

Sjögren's syndrome is an autoimmune disorder characterized by dry eyes and dry mouth due to the destruction of the glands that produce saliva and tears. In the context of complete dentures, xerostomia, or dry mouth, plays a crucial role in how well dentures function and fit. Adequate saliva is essential for maintaining oral health and ensuring that dentures adhere properly to the oral mucosa.

Patients with Sjögren's syndrome often experience significant discomfort and difficulty with complete dentures because the lack of saliva can lead to increased friction, making it harder for the dentures to stay in place. This results in an increase in wear and potential damage over time. Therefore, Sjögren's syndrome significantly impacts the longevity and effectiveness of complete dentures due to its direct influence on salivary production and oral moisture.

In contrast, while xerostomia alone can affect dentures, Sjögren's syndrome encompasses this condition along with other systemic issues. Rheumatoid arthritis and diabetes mellitus can have oral manifestations, but their effects on denture wear are not as pronounced as those seen with Sjögren's syndrome.